Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALOX15B	HGNC:434 (HGNC) 247 (Entrez Gene) 603697 (OMIM) ALOX15B (Alliance of Genome Resources)	Chr17 p13.1	Chr17:8039034-8049134 (+) GRCh38		O15296 (UniProt | EBI) NM_001141 (RefSeq)
mouse	Alox8	MGI:1098228 (MGI) 11688 (Entrez Gene) Gene Tree Alox8 (Alliance of Genome Resources)	Chr11 42.38 cM	Chr11:69074758-69088669 (-) GRCm39		ENSMUSG00000020891 (Ensembl Gene Model) ENSMUSP00000021262 (Ensembl) ENSMUST00000021262 (Ensembl)
rat	Alox15b	RGD:628809 (Rat Genome Database) 266604 (Entrez Gene) Alox15b (Alliance of Genome Resources)	Chr10 q24			Q8K4F2 (UniProt | EBI) NM_153301 (RefSeq)
zebrafish	si:dkey-17e16.9	ZDB-GENE-091118-123 (Zebrafish Model Organism Database) 794132 (Entrez Gene) si:dkey-17e16.9 (Alliance of Genome Resources)	Chr21			XP_017208558 (RefSeq)
	zgc:152891	ZDB-GENE-061013-229 (Zebrafish Model Organism Database) 767741 (Entrez Gene) zgc:152891 (Alliance of Genome Resources)	Chr21			NP_001070178 (RefSeq) NM_001076710 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.