Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TFAM	HGNC:11741 (HGNC) 7019 (Entrez Gene) 600438 (OMIM) TFAM (Alliance of Genome Resources)	Chr10 q21.1	Chr10:58385345-58399220 (+) GRCh38	Alzheimer's disease amyotrophic lateral sclerosis Huntington's disease mitochondrial DNA depletion syndrome 15 Parkinson's disease	Q00059 (UniProt | EBI) NM_003201 (RefSeq)
mouse	Tfam	MGI:107810 (MGI) 21780 (Entrez Gene) Gene Tree Tfam (Alliance of Genome Resources)	Chr10 36.83 cM	Chr10:71061294-71074110 (-) GRCm39	Kearns-Sayre syndrome Parkinson's disease	ENSMUSG00000003923 (Ensembl Gene Model) ENSMUSP00000090086 (Ensembl) ENSMUST00000092430 (Ensembl)
rat	Tfam	RGD:620682 (Rat Genome Database) 83474 (Entrez Gene) Tfam (Alliance of Genome Resources)	Chr20 p11			Q91ZW1 (UniProt | EBI) NM_031326 (RefSeq)
zebrafish	tfam	ZDB-GENE-061013-552 (Zebrafish Model Organism Database) 571106 (Entrez Gene) tfam (Alliance of Genome Resources)	Chr12			NP_001070857 (RefSeq) NM_001077389 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.