Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FOXO1	HGNC:3819 (HGNC) 2308 (Entrez Gene) 136533 (OMIM) FOXO1 (Alliance of Genome Resources)	Chr13 q14.11	Chr13:40555667-40666641 (-) GRCh38	alveolar rhabdomyosarcoma	Q12778 (UniProt | EBI) NM_002015 (RefSeq)
mouse	Foxo1	MGI:1890077 (MGI) 56458 (Entrez Gene) Gene Tree Foxo1 (Alliance of Genome Resources)	Chr3 23.19 cM	Chr3:52175758-52257530 (+) GRCm39		56458 (NCBI Gene Model) Q9R1E0 (UniProt | EBI) NM_019739 (RefSeq)
rat	Foxo1	RGD:620283 (Rat Genome Database) 84482 (Entrez Gene) Foxo1 (Alliance of Genome Resources)	Chr2 q26			G3V7R4 (UniProt | EBI) NM_001191846 (RefSeq)
zebrafish	foxo1a	ZDB-GENE-061013-59 (Zebrafish Model Organism Database) 768121 (Entrez Gene) foxo1a (Alliance of Genome Resources)	Chr15			A3RK74 (UniProt | EBI) NM_001077257 (RefSeq)
	foxo1b	ZDB-GENE-080425-3 (Zebrafish Model Organism Database) 567969 (Entrez Gene) foxo1b (Alliance of Genome Resources)	Chr10			A3RK75 (UniProt | EBI) NM_001082857 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.