Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ECE1	HGNC:3146 (HGNC) 1889 (Entrez Gene) 600423 (OMIM) ECE1 (Alliance of Genome Resources)	Chr1 p36.12	Chr1:21217247-21345572 (-) GRCh38	Alzheimer's disease coronary artery disease essential hypertension hypertension	P42892 (UniProt | EBI) NM_001113348 (RefSeq)
mouse	Ece1	MGI:1101357 (MGI) 230857 (Entrez Gene) Gene Tree Ece1 (Alliance of Genome Resources)	Chr4 70.02 cM	Chr4:137589548-137692540 (+) GRCm39	double outlet right ventricle	230857 (NCBI Gene Model) Q4PZA2 (UniProt | EBI) NM_199307 (RefSeq)
rat	Ece1	RGD:620293 (Rat Genome Database) 94204 (Entrez Gene) Ece1 (Alliance of Genome Resources)	Chr5 q36			P42893 (UniProt | EBI) NM_053596 (RefSeq)
zebrafish	ece1	ZDB-GENE-061110-100 (Zebrafish Model Organism Database) 777750 (Entrez Gene) ece1 (Alliance of Genome Resources)	Chr11			NP_001071260 (RefSeq) NM_001077792 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.