Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DKK3	HGNC:2893 (HGNC) 27122 (Entrez Gene) 605416 (OMIM) DKK3 (Alliance of Genome Resources)	Chr11 p15.3	Chr11:11956207-12009769 (-) GRCh38		Q9UBP4 (UniProt | EBI) NM_015881 (RefSeq)
mouse	Dkk3	MGI:1354952 (MGI) 50781 (Entrez Gene) Gene Tree Dkk3 (Alliance of Genome Resources)	Chr7 58.74 cM	Chr7:111715224-111758264 (-) GRCm39		ENSMUSG00000030772 (Ensembl Gene Model) ENSMUSP00000033036 (Ensembl) ENSMUST00000033036 (Ensembl)
rat	Dkk3	RGD:621846 (Rat Genome Database) 171548 (Entrez Gene) Dkk3 (Alliance of Genome Resources)	Chr1 q33			NP_612528 (RefSeq) NM_138519 (RefSeq)
zebrafish	dkk3a	ZDB-GENE-110519-1 (Zebrafish Model Organism Database) 570418 (Entrez Gene) dkk3a (Alliance of Genome Resources)	Chr7			NP_001152755 (RefSeq) NM_001159283 (RefSeq)
	dkk3b	ZDB-GENE-061207-74 (Zebrafish Model Organism Database) 100038765 (Entrez Gene) dkk3b (Alliance of Genome Resources)	Chr25			NP_001083014 (RefSeq) NM_001089545 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.