Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ELN	HGNC:3327 (HGNC) 2006 (Entrez Gene) 130160 (OMIM) ELN (Alliance of Genome Resources)	Chr7 q11.23	Chr7:74027789-74069907 (+) GRCh38	abdominal aortic aneurysm aortic aneurysm aortic valve stenosis autosomal dominant cutis laxa 1 chronic obstructive pulmonary disease cutis laxa dermatitis herpetiformis diabetic retinopathy Kuhnt-Junius degeneration polyarteritis nodosa polymyositis pseudoxanthoma elasticum rheumatoid arthritis supravalvular aortic stenosis systemic lupus erythematosus systemic scleroderma temporal arteritis Williams-Beuren syndrome	P15502 (UniProt | EBI) NM_001278939 (RefSeq)
mouse	Eln	MGI:95317 (MGI) 13717 (Entrez Gene) Gene Tree Eln (Alliance of Genome Resources)	Chr5 74.76 cM	Chr5:134731447-134776177 (-) GRCm39	aortic valve disease essential hypertension supravalvular aortic stenosis	ENSMUSG00000029675 (Ensembl Gene Model) ENSMUSP00000015138 (Ensembl) ENSMUST00000015138 (Ensembl)
rat	Eln	RGD:67394 (Rat Genome Database) 25043 (Entrez Gene) Eln (Alliance of Genome Resources)	Chr12 q12			Q99372 (UniProt | EBI) NM_012722 (RefSeq)
zebrafish	elna	ZDB-GENE-061212-1 (Zebrafish Model Organism Database) 790915 (Entrez Gene) elna (Alliance of Genome Resources)	Chr15			NP_001073532 (RefSeq) NM_001080063 (RefSeq)
	elnb	ZDB-GENE-061212-2 (Zebrafish Model Organism Database) 558461 (Entrez Gene) elnb (Alliance of Genome Resources)	Chr21			NP_001041529 (RefSeq) NM_001048064 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.