Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NRXN1	HGNC:8008 (HGNC) 9378 (Entrez Gene) 600565 (OMIM) NRXN1 (Alliance of Genome Resources)	Chr2 p16.3	Chr2:49918503-51225575 (-) GRCh38	Pitt-Hopkins-like syndrome 2	P58400 (UniProt | EBI) NM_001330094 (RefSeq)
mouse	Nrxn1	MGI:1096391 (MGI) 18189 (Entrez Gene) Gene Tree Nrxn1 (Alliance of Genome Resources)	Chr17 59.73 cM	Chr17:90341059-91400499 (-) GRCm39	autism spectrum disorder schizophrenia	ENSMUSG00000024109 (Ensembl Gene Model) ENSMUSP00000124116 (Ensembl) ENSMUST00000161402 (Ensembl)
rat	Nrxn1	RGD:628659 (Rat Genome Database) 60391 (Entrez Gene) Nrxn1 (Alliance of Genome Resources)	Chr6 q11-q12			Q63373 (UniProt | EBI) NM_021767 (RefSeq)
zebrafish	nrxn1a	ZDB-GENE-070206-1 (Zebrafish Model Organism Database) 565531 (Entrez Gene) nrxn1a (Alliance of Genome Resources)	Chr12			A1XQX0 (UniProt | EBI) NM_001346924 (RefSeq)
	nrxn1b	ZDB-GENE-070206-3 (Zebrafish Model Organism Database) 555686 (Entrez Gene) nrxn1b (Alliance of Genome Resources)	Chr13			A1XQX2 (UniProt | EBI) NM_001079959 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.