Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	COL11A1	HGNC:2186 (HGNC) 1301 (Entrez Gene) 120280 (OMIM) COL11A1 (Alliance of Genome Resources)	Chr1 p21.1	Chr1:102876467-103108872 (-) GRCh38	autosomal dominant nonsyndromic deafness fibrochondrogenesis 1 Marshall syndrome Stickler syndrome 2	P12107 (UniProt | EBI) NM_001854 (RefSeq)
mouse	Col11a1	MGI:88446 (MGI) 12814 (Entrez Gene) Gene Tree Col11a1 (Alliance of Genome Resources)	Chr3 49.35 cM	Chr3:113824189-114014367 (+) GRCm39	osteoarthritis Stickler syndrome	ENSMUSG00000027966 (Ensembl Gene Model) ENSMUSP00000089793 (Ensembl) ENSMUST00000092155 (Ensembl)
rat	Col11a1	RGD:2372 (Rat Genome Database) 25654 (Entrez Gene) Col11a1 (Alliance of Genome Resources)	Chr2 q42			P20909 (UniProt | EBI) NM_013117 (RefSeq)
zebrafish	col11a1a	ZDB-GENE-070209-167 (Zebrafish Model Organism Database) 565402 (Entrez Gene) col11a1a (Alliance of Genome Resources)	Chr24			NP_001077313 (RefSeq) NM_001083844 (RefSeq)
	col11a1b	ZDB-GENE-070912-607 (Zebrafish Model Organism Database) 555202 (Entrez Gene) col11a1b (Alliance of Genome Resources)	Chr2			NP_001171883 (RefSeq) NM_001184954 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.