Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RXRA	HGNC:10477 (HGNC) 6256 (Entrez Gene) 180245 (OMIM) RXRA (Alliance of Genome Resources)	Chr9 q34.2	Chr9:134317098-134440585 (+) GRCh38	pancreatic cancer	P19793 (UniProt | EBI) NM_001291920 (RefSeq)
mouse	Rxra	MGI:98214 (MGI) 20181 (Entrez Gene) Gene Tree Rxra (Alliance of Genome Resources)	Chr2 19.38 cM	Chr2:27566452-27652969 (+) GRCm39	congenital heart disease dilated cardiomyopathy systemic lupus erythematosus	ENSMUSG00000015846 (Ensembl Gene Model) ENSMUSP00000159198 (Ensembl) ENSMUST00000238913 (Ensembl)
rat	Rxra	RGD:3610 (Rat Genome Database) 25271 (Entrez Gene) Rxra (Alliance of Genome Resources)	Chr3 p12			Q05343 (UniProt | EBI) NM_012805 (RefSeq)
zebrafish	rxraa	ZDB-GENE-070314-2 (Zebrafish Model Organism Database) 555578 (Entrez Gene) rxraa (Alliance of Genome Resources)	Chr21			A2T929 (UniProt | EBI) NM_001161551 (RefSeq)
	rxrab	ZDB-GENE-990415-243 (Zebrafish Model Organism Database) 793011 (Entrez Gene) rxrab (Alliance of Genome Resources)	Chr5			Q90415 (UniProt | EBI) NM_131153 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.