Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FASLG	HGNC:11936 (HGNC) 356 (Entrez Gene) 134638 (OMIM) FASLG (Alliance of Genome Resources)	Chr1 q24.3	Chr1:172659103-172666876 (+) GRCh38	autoimmune lymphoproliferative syndrome cholangiocarcinoma chronic myeloid leukemia HELLP syndrome lung cancer melanoma multiple sclerosis pancreatic cancer pancreatic ductal carcinoma pre-eclampsia type 2 diabetes mellitus urinary bladder cancer	P48023 (UniProt | EBI) NM_001302746 (RefSeq)
mouse	Fasl	MGI:99255 (MGI) 14103 (Entrez Gene) Gene Tree Fasl (Alliance of Genome Resources)	Chr1 69.95 cM	Chr1:161608260-161616064 (-) GRCm39	autoimmune lymphoproliferative syndrome type 1 diabetes mellitus	14103 (NCBI Gene Model) P41047 (UniProt | EBI) NM_010177 (RefSeq)
rat	Faslg	RGD:3880 (Rat Genome Database) 25385 (Entrez Gene) Faslg (Alliance of Genome Resources)	Chr13 q22			P36940 (UniProt | EBI) NM_012908 (RefSeq)
zebrafish	faslg	ZDB-GENE-070410-16 (Zebrafish Model Organism Database) 735295 (Entrez Gene) faslg (Alliance of Genome Resources)	Chr20			NP_001036166 (RefSeq) NM_001042701 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.