Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RASGRP3	HGNC:14545 (HGNC) 25780 (Entrez Gene) 609531 (OMIM) RASGRP3 (Alliance of Genome Resources)	Chr2 p22.3	Chr2:33436324-33564750 (+) GRCh38	hypertension	Q8IV61 (UniProt | EBI) NM_001349979 (RefSeq)
mouse	Rasgrp3	MGI:3028579 (MGI) 240168 (Entrez Gene) Gene Tree Rasgrp3 (Alliance of Genome Resources)	Chr17 46.55 cM	Chr17:75742891-75836049 (+) GRCm39		ENSMUSG00000071042 (Ensembl Gene Model) ENSMUSP00000129393 (Ensembl) ENSMUST00000164192 (Ensembl)
rat	Rasgrp3	RGD:1304612 (Rat Genome Database) 313874 (Entrez Gene) Rasgrp3 (Alliance of Genome Resources)	Chr6 q12-q13			NP_001386473 (RefSeq) NM_001399544 (RefSeq)
zebrafish	rasgrp3	ZDB-GENE-070424-82 (Zebrafish Model Organism Database) 563441 (Entrez Gene) rasgrp3 (Alliance of Genome Resources)	Chr17			NP_001103934 (RefSeq) NM_001110464 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.