Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ARHGEF12	HGNC:14193 (HGNC) 23365 (Entrez Gene) 604763 (OMIM) ARHGEF12 (Alliance of Genome Resources)	Chr11 q23.3	Chr11:120336413-120489937 (+) GRCh38		Q9NZN5 (UniProt | EBI) NM_015313 (RefSeq)
mouse	Arhgef12	MGI:1916882 (MGI) 69632 (Entrez Gene) Gene Tree Arhgef12 (Alliance of Genome Resources)	Chr9 24.14 cM	Chr9:42875138-43017069 (-) GRCm39		69632 (NCBI Gene Model) Q8R4H2 (UniProt | EBI) NM_027144 (RefSeq)
rat	Arhgef12	RGD:1305111 (Rat Genome Database) 367072 (Entrez Gene) Arhgef12 (Alliance of Genome Resources)	Chr8 q22			NP_001013264 (RefSeq) NM_001013246 (RefSeq)
zebrafish	arhgef12a	ZDB-GENE-121017-3 (Zebrafish Model Organism Database) 562455 (Entrez Gene) arhgef12a (Alliance of Genome Resources)	Chr15			XP_009290008 (RefSeq)
	arhgef12b	ZDB-GENE-070705-36 (Zebrafish Model Organism Database) 571031 (Entrez Gene) arhgef12b (Alliance of Genome Resources)	Chr5			XP_009300160 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.