Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TIMP4	HGNC:11823 (HGNC) 7079 (Entrez Gene) 601915 (OMIM) TIMP4 (Alliance of Genome Resources)	Chr3 p25.2	Chr3:12153068-12158912 (-) GRCh38	nephroblastoma	Q99727 (UniProt | EBI) NM_003256 (RefSeq)
mouse	Timp4	MGI:109125 (MGI) 110595 (Entrez Gene) Gene Tree Timp4 (Alliance of Genome Resources)	Chr6 53.29 cM	Chr6:115221405-115229166 (-) GRCm39		110595 (NCBI Gene Model) Q9JHB3 (UniProt | EBI) NM_080639 (RefSeq)
rat	Timp4	RGD:69077 (Rat Genome Database) 680130 (Entrez Gene) Timp4 (Alliance of Genome Resources)	Chr4 q42			P81556 (UniProt | EBI) NM_001109393 (RefSeq)
zebrafish	timp4.1	ZDB-GENE-100603-1 (Zebrafish Model Organism Database) 101882922 (Entrez Gene) timp4.1 (Alliance of Genome Resources)	Chr11			XP_005172816 (RefSeq)
	timp4.2	ZDB-GENE-160114-61 (Zebrafish Model Organism Database) 108004535 (Entrez Gene) timp4.2 (Alliance of Genome Resources)	Chr11			NP_001315189 (RefSeq) NM_001328260 (RefSeq)
	timp4.3	ZDB-GENE-070824-1 (Zebrafish Model Organism Database) 100124610 (Entrez Gene) timp4.3 (Alliance of Genome Resources)	Chr11			NP_001313362 (RefSeq) NM_001326433 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.