Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HTR2A	HGNC:5293 (HGNC) 3356 (Entrez Gene) 182135 (OMIM) HTR2A (Alliance of Genome Resources)	Chr13 q14.2	Chr13:46831546-46898082 (-) GRCh38	alcohol dependence alcoholic psychosis chronic obstructive pulmonary disease cocaine dependence hypertension major depressive disorder nicotine dependence obesity obsessive-compulsive disorder pathological gambling schizophrenia steatotic liver disease withdrawal disorder	P28223 (UniProt | EBI) NM_001378924 (RefSeq)
mouse	Htr2a	MGI:109521 (MGI) 15558 (Entrez Gene) Gene Tree Htr2a (Alliance of Genome Resources)	Chr14 39.37 cM	Chr14:74878314-74944299 (+) GRCm39		15558 (NCBI Gene Model) P35363 (UniProt | EBI) NM_172812 (RefSeq)
rat	Htr2a	RGD:61800 (Rat Genome Database) 29595 (Entrez Gene) Htr2a (Alliance of Genome Resources)	Chr15 q11			P14842 (UniProt | EBI) NM_017254 (RefSeq)
zebrafish	htr2aa	ZDB-GENE-070912-500 (Zebrafish Model Organism Database) 560808 (Entrez Gene) htr2aa (Alliance of Genome Resources)	Chr9			XP_689300 (RefSeq)
	htr2ab	ZDB-GENE-120215-60 (Zebrafish Model Organism Database) 559806 (Entrez Gene) htr2ab (Alliance of Genome Resources)	Chr6			XP_009300470 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.