Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KCNH2	HGNC:6251 (HGNC) 3757 (Entrez Gene) 152427 (OMIM) KCNH2 (Alliance of Genome Resources)	Chr7 q36.1	Chr7:150944961-150978321 (-) GRCh38	long QT syndrome long QT syndrome 2 short QT syndrome	Q12809 (UniProt | EBI) NM_000238 (RefSeq)
mouse	Kcnh2	MGI:1341722 (MGI) 16511 (Entrez Gene) Gene Tree Kcnh2 (Alliance of Genome Resources)	Chr5 10.94 cM	Chr5:24524587-24556602 (-) GRCm39	short QT syndrome	ENSMUSG00000038319 (Ensembl Gene Model) ENSMUSP00000047705 (Ensembl) ENSMUST00000036092 (Ensembl)
rat	Kcnh2	RGD:621414 (Rat Genome Database) 117018 (Entrez Gene) Kcnh2 (Alliance of Genome Resources)	Chr4 q11			O08962 (UniProt | EBI) NM_053949 (RefSeq)
zebrafish	kcnh2a	ZDB-GENE-070912-699 (Zebrafish Model Organism Database) 563802 (Entrez Gene) kcnh2a (Alliance of Genome Resources)	Chr2			NP_001036187 (RefSeq) NM_001042722 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.