Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IKBKB	HGNC:5960 (HGNC) 3551 (Entrez Gene) 603258 (OMIM) IKBKB (Alliance of Genome Resources)	Chr8 p11.21	Chr8:42271302-42332460 (+) GRCh38	breast cancer dermatitis immunodeficiency 15A immunodeficiency 15B liver cancer prostate adenocarcinoma prostate cancer type 2 diabetes mellitus	O14920 (UniProt | EBI) NM_001556 (RefSeq)
mouse	Ikbkb	MGI:1338071 (MGI) 16150 (Entrez Gene) Gene Tree Ikbkb (Alliance of Genome Resources)	Chr8 11.42 cM	Chr8:23149228-23196605 (-) GRCm39	immunodeficiency 15A	16150 (NCBI Gene Model) O88351 (UniProt | EBI) NM_010546 (RefSeq)
rat	Ikbkb	RGD:621375 (Rat Genome Database) 84351 (Entrez Gene) Ikbkb (Alliance of Genome Resources)	Chr16 q12.5			Q9QY78 (UniProt | EBI) NM_053355 (RefSeq)
zebrafish	ikbkb	ZDB-GENE-071115-2 (Zebrafish Model Organism Database) 563560 (Entrez Gene) ikbkb (Alliance of Genome Resources)	Chr8			NP_001116737 (RefSeq) NM_001123265 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.