Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CIITA	HGNC:7067 (HGNC) 4261 (Entrez Gene) 600005 (OMIM) CIITA (Alliance of Genome Resources)	Chr16 p13.13	Chr16:10866206-10943021 (+) GRCh38	Addison's disease juvenile rheumatoid arthritis MHC class II deficiency multiple sclerosis myocardial infarction rheumatoid arthritis systemic lupus erythematosus	P33076 (UniProt | EBI) NM_001379332 (RefSeq)
mouse	Ciita	MGI:108445 (MGI) 12265 (Entrez Gene) Gene Tree Ciita (Alliance of Genome Resources)	Chr16 5.65 cM	Chr16:10297923-10346282 (+) GRCm39	MHC class II deficiency osteoporosis	ENSMUSG00000022504 (Ensembl Gene Model) ENSMUSP00000155517 (Ensembl) ENSMUST00000230395 (Ensembl)
rat	Ciita	RGD:619813 (Rat Genome Database) 85483 (Entrez Gene) Ciita (Alliance of Genome Resources)	Chr10 q11			NP_001257732 (RefSeq) NM_001270803 (RefSeq)
zebrafish	ciita	ZDB-GENE-071116-6 (Zebrafish Model Organism Database) 100003537 (Entrez Gene) ciita (Alliance of Genome Resources)	Chr3			XP_005163972 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.