Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ITGB3	HGNC:6156 (HGNC) 3690 (Entrez Gene) 173470 (OMIM) ITGB3 (Alliance of Genome Resources)	Chr17 q21.32	Chr17:47253827-47313743 (+) GRCh38	acute myeloid leukemia asthma autoimmune thrombocytopenic purpura blood platelet disease end stage renal disease Glanzmann's thrombasthenia myocardial infarction non-arteritic anterior ischemic optic neuropathy platelet-type bleeding disorder 16 thrombocytopenia	P05106 (UniProt | EBI) NM_000212 (RefSeq)
mouse	Itgb3	MGI:96612 (MGI) 16416 (Entrez Gene) Gene Tree Itgb3 (Alliance of Genome Resources)	Chr11 67.84 cM	Chr11:104498826-104561302 (+) GRCm39	Glanzmann's thrombasthenia platelet-type bleeding disorder 16	16416 (NCBI Gene Model) O54890 (UniProt | EBI) NM_016780 (RefSeq)
rat	Itgb3	RGD:628868 (Rat Genome Database) 29302 (Entrez Gene) Itgb3 (Alliance of Genome Resources)	Chr10			Q8R2H2 (UniProt | EBI) NM_153720 (RefSeq)
zebrafish	itgb3a	ZDB-GENE-071207-1 (Zebrafish Model Organism Database) 564266 (Entrez Gene) itgb3a (Alliance of Genome Resources)	Chr3			NP_001032312 (RefSeq) NM_001037235 (RefSeq)
	itgb3b	ZDB-GENE-071207-2 (Zebrafish Model Organism Database) 100001836 (Entrez Gene) itgb3b (Alliance of Genome Resources)	Chr12			NP_001076417 (RefSeq) NM_001082948 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.