Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL23R	HGNC:19100 (HGNC) 149233 (Entrez Gene) 607562 (OMIM) IL23R (Alliance of Genome Resources)	Chr1 p31.3	Chr1:67138637-67265903 (+) GRCh38	ankylosing spondylitis arthritis Behcet's disease celiac disease Crohn's disease Graves' disease Graves ophthalmopathy inflammatory bowel disease 17 multiple sclerosis osteonecrosis psoriasis psoriasis 7 pulmonary hypertension rheumatoid arthritis rhinitis sarcoidosis systemic scleroderma ulcerative colitis uveitis	Q5VWK5 (UniProt | EBI) NM_144701 (RefSeq)
mouse	Il23r	MGI:2181693 (MGI) 209590 (Entrez Gene) Gene Tree Il23r (Alliance of Genome Resources)	Chr6 30.85 cM	Chr6:67399916-67468839 (-) GRCm39		ENSMUSG00000049093 (Ensembl Gene Model) ENSMUSP00000113342 (Ensembl) ENSMUST00000118364 (Ensembl)
rat	Il23r	RGD:1586368 (Rat Genome Database) 689932 (Entrez Gene) Il23r (Alliance of Genome Resources)	Chr4 q31			NP_001418851 (RefSeq) NM_001431922 (RefSeq)
zebrafish	il23r	ZDB-GENE-080107-5 (Zebrafish Model Organism Database) 100134972 (Entrez Gene) il23r (Alliance of Genome Resources)	Chr6			NP_001106978 (RefSeq) NM_001113506 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.