Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FBXW8	HGNC:13597 (HGNC) 26259 (Entrez Gene) 609073 (OMIM) FBXW8 (Alliance of Genome Resources)	Chr12 q24.22	Chr12:116910950-117031148 (+) GRCh38		Q8N3Y1 (UniProt | EBI) NM_153348 (RefSeq)
mouse	Fbxw8	MGI:1923041 (MGI) 231672 (Entrez Gene) Gene Tree Fbxw8 (Alliance of Genome Resources)	Chr5 57.92 cM	Chr5:118203046-118293523 (-) GRCm39		231672 (NCBI Gene Model) Q8BIA4 (UniProt | EBI) NM_172721 (RefSeq)
rat	Fbxw8	RGD:1306032 (Rat Genome Database) 304522 (Entrez Gene) Fbxw8 (Alliance of Genome Resources)	Chr12 q16			P0DL28 (UniProt | EBI) NM_001107145 (RefSeq)
zebrafish	fbxw8	ZDB-GENE-080204-111 (Zebrafish Model Organism Database) 100136859 (Entrez Gene) fbxw8 (Alliance of Genome Resources)	Chr5			NP_001108050 (RefSeq) NM_001114578 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.