Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ABCB1	HGNC:40 (HGNC) 5243 (Entrez Gene) 171050 (OMIM) ABCB1 (Alliance of Genome Resources)	Chr7 q21.12	Chr7:87503017-87713323 (-) GRCh38	acquired immunodeficiency syndrome acute lymphoblastic leukemia allergic rhinitis antisocial personality disorder Behcet's disease cannabis dependence chronic myeloid leukemia colorectal adenocarcinoma Crohn's disease cryoglobulinemia drug dependence epilepsy familial hyperlipidemia familial Mediterranean fever hepatocellular carcinoma heroin dependence human immunodeficiency virus infectious disease inflammatory bowel disease 13 invasive ductal carcinoma lung non-small cell carcinoma malaria opiate dependence osteonecrosis pulmonary tuberculosis renal cell carcinoma toxic encephalopathy type 2 diabetes mellitus ulcerative colitis	P08183 (UniProt | EBI) NM_001348944 (RefSeq)
mouse	Abcb1a	MGI:97570 (MGI) 18671 (Entrez Gene) Gene Tree Abcb1a (Alliance of Genome Resources)	Chr5 3.43 cM	Chr5:8710077-8798575 (+) GRCm39	inflammatory bowel disease 13	ENSMUSG00000040584 (Ensembl Gene Model) ENSMUSP00000041204 (Ensembl) ENSMUST00000047753 (Ensembl)
zebrafish	abcb4	ZDB-GENE-080204-52 (Zebrafish Model Organism Database) 100136865 (Entrez Gene) abcb4 (Alliance of Genome Resources)	Chr16			NP_001108055 (RefSeq) NM_001114583 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.