Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WAPL	HGNC:23293 (HGNC) 23063 (Entrez Gene) 610754 (OMIM) WAPL (Alliance of Genome Resources)	Chr10 q23.2	Chr10:86435256-86521792 (-) GRCh38		Q7Z5K2 (UniProt | EBI) NM_015045 (RefSeq)
mouse	Wapl	MGI:2675859 (MGI) 218914 (Entrez Gene) Gene Tree Wapl (Alliance of Genome Resources)	Chr14 20.84 cM	Chr14:34395885-34469940 (+) GRCm39		ENSMUSG00000041408 (Ensembl Gene Model) ENSMUSP00000130547 (Ensembl) ENSMUST00000169910 (Ensembl)
rat	Wapl	RGD:1590924 (Rat Genome Database) 290577 (Entrez Gene) Wapl (Alliance of Genome Resources)	Chr16 p15			NP_001414208 (RefSeq) NM_001427279 (RefSeq)
zebrafish	wapla	ZDB-GENE-131010-1 (Zebrafish Model Organism Database) 553345 (Entrez Gene) wapla (Alliance of Genome Resources)	Chr17			XP_021328854 (RefSeq)
	waplb	ZDB-GENE-080220-45 (Zebrafish Model Organism Database) 100141368 (Entrez Gene) waplb (Alliance of Genome Resources)	Chr12			XP_021335944 (RefSeq) NM_001114932 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.