Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TERT	HGNC:11730 (HGNC) 7015 (Entrez Gene) 187270 (OMIM) TERT (Alliance of Genome Resources)	Chr5 p15.33	Chr5:1253147-1295068 (-) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia autosomal dominant dyskeratosis congenita 2 brain cancer esophagus squamous cell carcinoma familial melanoma gallbladder carcinoma gastrointestinal stromal tumor hepatocellular carcinoma idiopathic pulmonary fibrosis lung adenocarcinoma lung non-small cell carcinoma lung squamous cell carcinoma melanoma oral squamous cell carcinoma small cell carcinoma urinary bladder cancer	O14746 (UniProt | EBI) NM_001193376 (RefSeq)
mouse	Tert	MGI:1202709 (MGI) 21752 (Entrez Gene) Gene Tree Tert (Alliance of Genome Resources)	Chr13 40.12 cM	Chr13:73775030-73797962 (+) GRCm39		21752 (NCBI Gene Model) O70372 (UniProt | EBI) NM_009354 (RefSeq)
rat	Tert	RGD:70494 (Rat Genome Database) 301965 (Entrez Gene) Tert (Alliance of Genome Resources)	Chr1 p11			Q673L6 (UniProt | EBI) NM_001007019 (RefSeq)
zebrafish	tert	ZDB-GENE-080405-1 (Zebrafish Model Organism Database) 796551 (Entrez Gene) tert (Alliance of Genome Resources)	Chr19			NP_001077335 (RefSeq) NM_001083866 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.