Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF2AK2	HGNC:9437 (HGNC) 5610 (Entrez Gene) 176871 (OMIM) EIF2AK2 (Alliance of Genome Resources)	Chr2 p22.2	Chr2:37099210-37157522 (-) GRCh38	Alzheimer's disease dystonia 33 hepatitis B Huntington's disease Parkinson's disease	P19525 (UniProt | EBI) NM_002759 (RefSeq)
mouse	Eif2ak2	MGI:1353449 (MGI) 19106 (Entrez Gene) Gene Tree Eif2ak2 (Alliance of Genome Resources)	Chr17 49.56 cM	Chr17:79159993-79190002 (-) GRCm39		ENSMUSG00000024079 (Ensembl Gene Model) ENSMUSP00000024884 (Ensembl) ENSMUST00000024884 (Ensembl)
rat	Eif2ak2	RGD:3402 (Rat Genome Database) 54287 (Entrez Gene) Eif2ak2 (Alliance of Genome Resources)	Chr6 q12			Q63184 (UniProt | EBI) NM_019335 (RefSeq)
zebrafish	eif2ak2	ZDB-GENE-080422-1 (Zebrafish Model Organism Database) 100001092 (Entrez Gene) eif2ak2 (Alliance of Genome Resources)	Chr13			NP_001107942 (RefSeq) NM_001114470 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.