Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KMT2A	HGNC:7132 (HGNC) 4297 (Entrez Gene) 159555 (OMIM) KMT2A (Alliance of Genome Resources)	Chr11 q23.3	Chr11:118436456-118526832 (+) GRCh38	acute myeloid leukemia cervical cancer myelofibrosis non-Hodgkin lymphoma	Q03164 (UniProt | EBI) NM_005933 (RefSeq)
mouse	Kmt2a	MGI:96995 (MGI) 214162 (Entrez Gene) Gene Tree Kmt2a (Alliance of Genome Resources)	Chr9 24.84 cM	Chr9:44714652-44792594 (-) GRCm39	acute lymphoblastic leukemia acute myeloid leukemia	ENSMUSG00000002028 (Ensembl Gene Model) ENSMUSP00000110337 (Ensembl) ENSMUST00000114689 (Ensembl)
rat	Kmt2a	RGD:1586165 (Rat Genome Database) 315606 (Entrez Gene) Kmt2a (Alliance of Genome Resources)	Chr8 q22			NP_001101609 (RefSeq) NM_001419940 (RefSeq)
zebrafish	kmt2a	ZDB-GENE-080521-3 (Zebrafish Model Organism Database) 557048 (Entrez Gene) kmt2a (Alliance of Genome Resources)	Chr15			NP_001103749 (RefSeq) NM_001110279 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.