Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TMEM67	HGNC:28396 (HGNC) 91147 (Entrez Gene) 609884 (OMIM) TMEM67 (Alliance of Genome Resources)	Chr8 q22.1	Chr8:93754844-93832653 (+) GRCh38	Bardet-Biedl syndrome Bardet-Biedl syndrome 14 COACH syndrome coloboma Joubert syndrome 6 Meckel syndrome 3 nephronophthisis nephronophthisis 11 portal hypertension	Q5HYA8 (UniProt | EBI) NM_153704 (RefSeq)
mouse	Tmem67	MGI:1923928 (MGI) 329795 (Entrez Gene) Gene Tree Tmem67 (Alliance of Genome Resources)	Chr4 5.56 cM	Chr4:12039355-12090020 (-) GRCm39	cystic kidney disease Joubert syndrome 6 Meckel syndrome visceral heterotaxy	329795 (NCBI Gene Model) Q8BR76 (UniProt | EBI) NR_110955 (RefSeq)
rat	Tmem67	RGD:1586167 (Rat Genome Database) 313067 (Entrez Gene) Tmem67 (Alliance of Genome Resources)	Chr5 q13			P0C152 (UniProt | EBI) NM_001107916 (RefSeq)
zebrafish	tmem67	ZDB-GENE-080716-1 (Zebrafish Model Organism Database) 572194 (Entrez Gene) tmem67 (Alliance of Genome Resources)	Chr16			XP_700974 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.