Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PAX3	HGNC:8617 (HGNC) 5077 (Entrez Gene) 606597 (OMIM) PAX3 (Alliance of Genome Resources)	Chr2 q36.1	Chr2:222199887-222298998 (-) GRCh38	alveolar rhabdomyosarcoma craniofacial-deafness-hand syndrome Waardenburg syndrome Waardenburg syndrome type 1 Waardenburg syndrome type 3	P23760 (UniProt | EBI) NM_013942 (RefSeq)
mouse	Pax3	MGI:97487 (MGI) 18505 (Entrez Gene) Gene Tree Pax3 (Alliance of Genome Resources)	Chr1 39.79 cM	Chr1:78077904-78173771 (-) GRCm39	neural tube defect Waardenburg syndrome type 1	ENSMUSG00000004872 (Ensembl Gene Model) ENSMUSP00000004994 (Ensembl) ENSMUST00000004994 (Ensembl)
rat	Pax3	RGD:620431 (Rat Genome Database) 114502 (Entrez Gene) Pax3 (Alliance of Genome Resources)	Chr9 q33			NP_446162 (RefSeq) NM_053710 (RefSeq)
zebrafish	pax3a	ZDB-GENE-980526-52 (Zebrafish Model Organism Database) 30532 (Entrez Gene) pax3a (Alliance of Genome Resources)	Chr2			NP_571352 (RefSeq) NM_131277 (RefSeq)
	pax3b	ZDB-GENE-080917-53 (Zebrafish Model Organism Database) 100150137 (Entrez Gene) pax3b (Alliance of Genome Resources)	Chr15			NP_001315326 (RefSeq) NM_001328397 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.