Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	APPL2	HGNC:18242 (HGNC) 55198 (Entrez Gene) 606231 (OMIM) APPL2 (Alliance of Genome Resources)	Chr12 q23.3	Chr12:105173297-105236203 (-) GRCh38		Q8NEU8 (UniProt | EBI) NM_001251905 (RefSeq)
mouse	Appl2	MGI:2384914 (MGI) 216190 (Entrez Gene) Gene Tree Appl2 (Alliance of Genome Resources)	Chr10 41.29 cM	Chr10:83435897-83484602 (-) GRCm39		ENSMUSG00000020263 (Ensembl Gene Model) ENSMUSP00000020500 (Ensembl) ENSMUST00000020500 (Ensembl)
rat	Appl2	RGD:1563028 (Rat Genome Database) 362860 (Entrez Gene) Appl2 (Alliance of Genome Resources)	Chr7 q13			B4F779 (UniProt | EBI) NM_001108741 (RefSeq)
zebrafish	appl2	ZDB-GENE-081016-2 (Zebrafish Model Organism Database) 100000135 (Entrez Gene) appl2 (Alliance of Genome Resources)	Chr25			NP_001121547 (RefSeq) NM_001128075 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.