Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLEKHM2	HGNC:29131 (HGNC) 23207 (Entrez Gene) 609613 (OMIM) PLEKHM2 (Alliance of Genome Resources)	Chr1 p36.21	Chr1:15681506-15734769 (+) GRCh38		Q8IWE5 (UniProt | EBI) NM_001410755 (RefSeq)
mouse	Plekhm2	MGI:1916832 (MGI) 69582 (Entrez Gene) Gene Tree Plekhm2 (Alliance of Genome Resources)	Chr4 74.64 cM	Chr4:141353043-141391457 (-) GRCm39		69582 (NCBI Gene Model) Q80TQ5 (UniProt | EBI) NM_001033150 (RefSeq)
rat	Plekhm2	RGD:1307005 (Rat Genome Database) 313667 (Entrez Gene) Plekhm2 (Alliance of Genome Resources)	Chr5 q36			NP_001178696 (RefSeq) NM_001191767 (RefSeq)
zebrafish	plekhm2	ZDB-GENE-081022-169 (Zebrafish Model Organism Database) 564823 (Entrez Gene) plekhm2 (Alliance of Genome Resources)	Chr23			NP_001124255 (RefSeq) NM_001130783 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.