Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HTR2B	HGNC:5294 (HGNC) 3357 (Entrez Gene) 601122 (OMIM) HTR2B (Alliance of Genome Resources)	Chr2 q37.1	Chr2:231108230-231125042 (-) GRCh38	metabolic dysfunction-associated steatohepatitis steatotic liver disease	P41595 (UniProt | EBI) NM_001320758 (RefSeq)
mouse	Htr2b	MGI:109323 (MGI) 15559 (Entrez Gene) Gene Tree Htr2b (Alliance of Genome Resources)	Chr1 43.94 cM	Chr1:86026748-86039692 (-) GRCm39	hypertrophic cardiomyopathy	ENSMUSG00000026228 (Ensembl Gene Model) ENSMUSP00000027431 (Ensembl) ENSMUST00000027431 (Ensembl)
rat	Htr2b	RGD:61801 (Rat Genome Database) 29581 (Entrez Gene) Htr2b (Alliance of Genome Resources)	Chr9 q35			P30994 (UniProt | EBI) NM_017250 (RefSeq)
zebrafish	htr2b	ZDB-GENE-081022-57 (Zebrafish Model Organism Database) 751784 (Entrez Gene) htr2b (Alliance of Genome Resources)	Chr22			NP_001038208 (RefSeq) NM_001044743 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.