Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DNM1	HGNC:2972 (HGNC) 1759 (Entrez Gene) 602377 (OMIM) DNM1 (Alliance of Genome Resources)	Chr9 q34.11	Chr9:128191655-128255248 (+) GRCh38	developmental and epileptic encephalopathy 31A developmental and epileptic encephalopathy 31B	Q05193 (UniProt | EBI) NM_004408 (RefSeq)
mouse	Dnm1	MGI:107384 (MGI) 13429 (Entrez Gene) Gene Tree Dnm1 (Alliance of Genome Resources)	Chr2 22.09 cM	Chr2:32198483-32243350 (-) GRCm39	idiopathic generalized epilepsy	ENSMUSG00000026825 (Ensembl Gene Model) ENSMUSP00000122679 (Ensembl) ENSMUST00000139624 (Ensembl)
rat	Dnm1	RGD:71096 (Rat Genome Database) 140694 (Entrez Gene) Dnm1 (Alliance of Genome Resources)	Chr3 p12			P21575 (UniProt | EBI) NM_080689 (RefSeq)
zebrafish	dnm1a	ZDB-GENE-081104-27 (Zebrafish Model Organism Database) 100307098 (Entrez Gene) dnm1a (Alliance of Genome Resources)	Chr5			NP_001232894 (RefSeq) NM_001245965 (RefSeq)
	dnm1b	ZDB-GENE-100920-3 (Zebrafish Model Organism Database) 100333543 (Entrez Gene) dnm1b (Alliance of Genome Resources)	Chr5			NP_001243747 (RefSeq) NM_001256818 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.