Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CDKN2B	HGNC:1788 (HGNC) 1030 (Entrez Gene) 600431 (OMIM) CDKN2B (Alliance of Genome Resources)	Chr9 p21.3	Chr9:22002903-22009313 (-) GRCh38	acute myeloid leukemia acute promyelocytic leukemia chronic myelomonocytic leukemia erythema infectiosum esophagus squamous cell carcinoma lung non-small cell carcinoma myelodysplastic syndrome open-angle glaucoma primary cutaneous T-cell non-Hodgkin lymphoma transitional cell carcinoma urinary bladder cancer	P42772 (UniProt | EBI) NM_078487 (RefSeq)
mouse	Cdkn2b	MGI:104737 (MGI) 12579 (Entrez Gene) Gene Tree Cdkn2b (Alliance of Genome Resources)	Chr4 42.15 cM	Chr4:89224536-89229276 (-) GRCm39		ENSMUSG00000073802 (Ensembl Gene Model) ENSMUSP00000095595 (Ensembl) ENSMUST00000097981 (Ensembl)
rat	Cdkn2b	RGD:2324 (Rat Genome Database) 25164 (Entrez Gene) Cdkn2b (Alliance of Genome Resources)	Chr5 q32			P55272 (UniProt | EBI) NM_130812 (RefSeq)
zebrafish	cdkn2a/b	ZDB-GENE-081104-306 (Zebrafish Model Organism Database) 100329528 (Entrez Gene) cdkn2a/b (Alliance of Genome Resources)	Chr1			XP_002660514 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.