Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CDKN2A	HGNC:1787 (HGNC) 1029 (Entrez Gene) 600160 (OMIM) CDKN2A (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21967752-21995324 (-) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia B-lymphoblastic leukemia/lymphoma breast cancer cervix uteri carcinoma in situ dysplastic nevus syndrome familial melanoma germinoma glioblastoma head and neck squamous cell carcinoma high grade glioma invasive ductal carcinoma leukemia melanoma melanoma and neural system tumor syndrome multiple myeloma myelodysplastic syndrome neurilemmoma neuroblastoma pancreatic adenocarcinoma pancreatic cancer pancreatic carcinoma primary cutaneous T-cell non-Hodgkin lymphoma prostate cancer renal cell carcinoma skin melanoma T-cell acute lymphoblastic leukemia transitional cell carcinoma urinary bladder cancer	Q8N726 (UniProt | EBI) NM_058196 (RefSeq)
mouse	Cdkn2a	MGI:104738 (MGI) 12578 (Entrez Gene) Gene Tree Cdkn2a (Alliance of Genome Resources)	Chr4 42.15 cM	Chr4:89192710-89212856 (-) GRCm39		12578 (NCBI Gene Model) Q64364 (UniProt | EBI) NM_009877 (RefSeq)
rat	Cdkn2a	RGD:2323 (Rat Genome Database) 25163 (Entrez Gene) Cdkn2a (Alliance of Genome Resources)	Chr5 q32			Q9R0Z3 (UniProt | EBI) NM_031550 (RefSeq)
zebrafish	cdkn2a/b	ZDB-GENE-081104-306 (Zebrafish Model Organism Database) 100329528 (Entrez Gene) cdkn2a/b (Alliance of Genome Resources)	Chr1			XP_002660514 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.