Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MFN2	HGNC:16877 (HGNC) 9927 (Entrez Gene) 608507 (OMIM) MFN2 (Alliance of Genome Resources)	Chr1 p36.22	Chr1:11980181-12015211 (+) GRCh38	Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease type 2A2A Charcot-Marie-Tooth disease type 2A2B Charcot-Marie-Tooth disease type 6 multiple symmetric lipomatosis	O95140 (UniProt | EBI) NM_001127660 (RefSeq)
mouse	Mfn2	MGI:2442230 (MGI) 170731 (Entrez Gene) Gene Tree Mfn2 (Alliance of Genome Resources)	Chr4 78.56 cM	Chr4:147958056-147989161 (-) GRCm39	Charcot-Marie-Tooth disease type 2A2A	ENSMUSG00000029020 (Ensembl Gene Model) ENSMUSP00000030884 (Ensembl) ENSMUST00000030884 (Ensembl)
rat	Mfn2	RGD:628843 (Rat Genome Database) 64476 (Entrez Gene) Mfn2 (Alliance of Genome Resources)	Chr5 q36			Q8R500 (UniProt | EBI) NM_001429967 (RefSeq)
zebrafish	mfn2	ZDB-GENE-081105-44 (Zebrafish Model Organism Database) 567448 (Entrez Gene) mfn2 (Alliance of Genome Resources)	Chr8			NP_001121726 (RefSeq) NM_001128254 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.