Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SYN1	HGNC:11494 (HGNC) 6853 (Entrez Gene) 313440 (OMIM) SYN1 (Alliance of Genome Resources)	ChrX p11.3-p11.23	ChrX:47571901-47619857 (-) GRCh38	non-syndromic X-linked intellectual disability 50 X-linked epilepsy with variable learning disabilities and behavior disorders	P17600 (UniProt | EBI) NM_133499 (RefSeq)
mouse	Syn1	MGI:98460 (MGI) 20964 (Entrez Gene) Gene Tree Syn1 (Alliance of Genome Resources)	ChrX 16.37 cM	ChrX:20726750-20787157 (-) GRCm39	autism spectrum disorder	20964 (NCBI Gene Model) O88935 (UniProt | EBI) NM_013680 (RefSeq)
rat	Syn1	RGD:3797 (Rat Genome Database) 24949 (Entrez Gene) Syn1 (Alliance of Genome Resources)	ChrX q11			P09951 (UniProt | EBI) NM_001110782 (RefSeq)
zebrafish	syn1	ZDB-GENE-081105-93 (Zebrafish Model Organism Database) 570672 (Entrez Gene) syn1 (Alliance of Genome Resources)	Chr8			NP_001119909 (RefSeq) NM_001126437 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.