Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRNA6	HGNC:15963 (HGNC) 8973 (Entrez Gene) 606888 (OMIM) CHRNA6 (Alliance of Genome Resources)	Chr8 p11.21	Chr8:42752620-42796392 (-) GRCh38	alcohol use disorder cocaine abuse nicotine dependence	Q15825 (UniProt | EBI) NM_004198 (RefSeq)
mouse	Chrna6	MGI:106213 (MGI) 11440 (Entrez Gene) Gene Tree Chrna6 (Alliance of Genome Resources)	Chr8 16.02 cM	Chr8:27893240-27903972 (-) GRCm39		11440 (NCBI Gene Model) Q9R0W9 (UniProt | EBI) NM_021369 (RefSeq)
rat	Chrna6	RGD:69281 (Rat Genome Database) 81721 (Entrez Gene) Chrna6 (Alliance of Genome Resources)	Chr16 q12.3			P43143 (UniProt | EBI) NM_057184 (RefSeq)
zebrafish	chrna6	ZDB-GENE-090312-91 (Zebrafish Model Organism Database) 555747 (Entrez Gene) chrna6 (Alliance of Genome Resources)	Chr1			NP_001036149 (RefSeq) NM_001042684 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.