Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAP3K1	HGNC:6848 (HGNC) 4214 (Entrez Gene) 600982 (OMIM) MAP3K1 (Alliance of Genome Resources)	Chr5 q11.2	Chr5:56815549-56896152 (+) GRCh38	46,XY sex reversal 6 breast cancer diffuse gastric cancer esophagus squamous cell carcinoma lung non-small cell carcinoma rectum cancer stomach cancer	Q13233 (UniProt | EBI) NM_005921 (RefSeq)
mouse	Map3k1	MGI:1346872 (MGI) 26401 (Entrez Gene) Gene Tree Map3k1 (Alliance of Genome Resources)	Chr13 63.36 cM	Chr13:111882962-111945527 (-) GRCm39		ENSMUSG00000021754 (Ensembl Gene Model) ENSMUSP00000104890 (Ensembl) ENSMUST00000109267 (Ensembl)
rat	Map3k1	RGD:620966 (Rat Genome Database) 116667 (Entrez Gene) Map3k1 (Alliance of Genome Resources)	Chr2 q14			Q62925 (UniProt | EBI) NM_053887 (RefSeq)
zebrafish	map3k1	ZDB-GENE-090313-412 (Zebrafish Model Organism Database) 100334486 (Entrez Gene) map3k1 (Alliance of Genome Resources)	Chr10			XP_005155564 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.