Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DNA2	HGNC:2939 (HGNC) 1763 (Entrez Gene) 601810 (OMIM) DNA2 (Alliance of Genome Resources)	Chr10 q21.3	Chr10:68414064-68472521 (-) GRCh38	autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6 isolated growth hormone deficiency type IA mitochondrial myopathy Seckel syndrome 8	P51530 (UniProt | EBI) NM_001080449 (RefSeq)
mouse	Dna2	MGI:2443732 (MGI) 327762 (Entrez Gene) Gene Tree Dna2 (Alliance of Genome Resources)	Chr10 32.51 cM	Chr10:62782805-62809964 (+) GRCm39		ENSMUSG00000036875 (Ensembl Gene Model) ENSMUSP00000115750 (Ensembl) ENSMUST00000131422 (Ensembl)
rat	Dna2	RGD:1306791 (Rat Genome Database) 309762 (Entrez Gene) Dna2 (Alliance of Genome Resources)	Chr20 q11			D3ZG52 (UniProt | EBI) NM_001389622 (RefSeq)
zebrafish	dna2	ZDB-GENE-090313-71 (Zebrafish Model Organism Database) 559535 (Entrez Gene) dna2 (Alliance of Genome Resources)	Chr13			XP_021336509 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.