Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CD40	HGNC:11919 (HGNC) 958 (Entrez Gene) 109535 (OMIM) CD40 (Alliance of Genome Resources)	Chr20 q13.12	Chr20:46118271-46129863 (+) GRCh38	arthritis asthma B-cell lymphoma Burkitt lymphoma Crohn's disease diffuse large B-cell lymphoma end stage renal disease follicular lymphoma Graves' disease hyperimmunoglobulin syndrome immunodeficiency with hyper IgM type 3 Kawasaki disease melanoma multiple myeloma multiple sclerosis non-Hodgkin lymphoma pancreatic ductal carcinoma pemphigus plasma cell leukemia psoriasis rheumatoid arthritis systemic lupus erythematosus	P25942 (UniProt | EBI) NM_001302753 (RefSeq)
mouse	Cd40	MGI:88336 (MGI) 21939 (Entrez Gene) Gene Tree Cd40 (Alliance of Genome Resources)	Chr2 85.38 cM	Chr2:164897535-164913574 (+) GRCm39		21939 (NCBI Gene Model) P27512 (UniProt | EBI) NR_027852 (RefSeq)
rat	Cd40	RGD:619830 (Rat Genome Database) 171369 (Entrez Gene) Cd40 (Alliance of Genome Resources)	Chr3 q42			NP_001418429 (RefSeq) NM_134360 (RefSeq)
zebrafish	cd40	ZDB-GENE-090313-95 (Zebrafish Model Organism Database) 100270764 (Entrez Gene) cd40 (Alliance of Genome Resources)	Chr23			NP_001138718 (RefSeq) NM_001145246 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.