Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MKKS	HGNC:7108 (HGNC) 8195 (Entrez Gene) 604896 (OMIM) MKKS (Alliance of Genome Resources)	Chr20 p12.2	Chr20:10401009-10434222 (-) GRCh38	Bardet-Biedl syndrome Bardet-Biedl syndrome 6 congenital heart disease McKusick-Kaufman syndrome obesity	Q9NPJ1 (UniProt | EBI) NM_170784 (RefSeq)
mouse	Mkks	MGI:1891836 (MGI) 59030 (Entrez Gene) Gene Tree Mkks (Alliance of Genome Resources)	Chr2 67.64 cM	Chr2:136715700-136733309 (-) GRCm39	Bardet-Biedl syndrome 6 obesity	ENSMUSG00000027274 (Ensembl Gene Model) ENSMUSP00000028730 (Ensembl) ENSMUST00000028730 (Ensembl)
rat	Mkks	RGD:1308814 (Rat Genome Database) 311456 (Entrez Gene) Mkks (Alliance of Genome Resources)	Chr3 q36			NP_001008354 (RefSeq) NM_001008353 (RefSeq)
zebrafish	mkks	ZDB-GENE-040426-757 (Zebrafish Model Organism Database) 393134 (Entrez Gene) mkks (Alliance of Genome Resources)	Chr13			NP_956459 (RefSeq) NM_200165 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.