Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRNA4	HGNC:1958 (HGNC) 1137 (Entrez Gene) 118504 (OMIM) CHRNA4 (Alliance of Genome Resources)	Chr20 q13.33	Chr20:63343223-63378401 (-) GRCh38	autosomal dominant nocturnal frontal lobe epilepsy 1 nicotine dependence	P43681 (UniProt | EBI) NM_001256573 (RefSeq)
mouse	Chrna4	MGI:87888 (MGI) 11438 (Entrez Gene) Gene Tree Chrna4 (Alliance of Genome Resources)	Chr2 103.54 cM	Chr2:180664104-180685339 (-) GRCm39		11438 (NCBI Gene Model) O70174 (UniProt | EBI) NM_015730 (RefSeq)
rat	Chrna4	RGD:2346 (Rat Genome Database) 25590 (Entrez Gene) Chrna4 (Alliance of Genome Resources)	Chr3 q43			P09483 (UniProt | EBI) NM_024354 (RefSeq)
zebrafish	chrna4b	ZDB-GENE-090505-3 (Zebrafish Model Organism Database) 556619 (Entrez Gene) chrna4b (Alliance of Genome Resources)	Chr11			NP_001041528 (RefSeq) NM_001048063 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.