Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PCSK2	HGNC:8744 (HGNC) 5126 (Entrez Gene) 162151 (OMIM) PCSK2 (Alliance of Genome Resources)	Chr20 p12.1	Chr20:17226107-17484578 (+) GRCh38	myocardial infarction type 2 diabetes mellitus	P16519 (UniProt | EBI) NM_002594 (RefSeq)
mouse	Pcsk2	MGI:97512 (MGI) 18549 (Entrez Gene) Gene Tree Pcsk2 (Alliance of Genome Resources)	Chr2 70.89 cM	Chr2:143388076-143658205 (+) GRCm39		ENSMUSG00000027419 (Ensembl Gene Model) ENSMUSP00000028905 (Ensembl) ENSMUST00000028905 (Ensembl)
rat	Pcsk2	RGD:3273 (Rat Genome Database) 25121 (Entrez Gene) Pcsk2 (Alliance of Genome Resources)	Chr3 q41			P28841 (UniProt | EBI) NM_012746 (RefSeq)
zebrafish	pcsk2	ZDB-GENE-090608-1 (Zebrafish Model Organism Database) 100004460 (Entrez Gene) pcsk2 (Alliance of Genome Resources)	Chr13			NP_001135738 (RefSeq) NM_001142266 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.