Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLEKHG3	HGNC:20364 (HGNC) 26030 (Entrez Gene) 617940 (OMIM) PLEKHG3 (Alliance of Genome Resources)	Chr14 q23.3	Chr14:64704102-64750249 (+) GRCh38		A1L390 (UniProt | EBI) NM_001308147 (RefSeq)
mouse	Plekhg3	MGI:2388284 (MGI) 263406 (Entrez Gene) Gene Tree Plekhg3 (Alliance of Genome Resources)	Chr12 33.73 cM	Chr12:76580330-76627265 (+) GRCm39		263406 (NCBI Gene Model) Q4VAC9 (UniProt | EBI) NM_153804 (RefSeq)
rat	Plekhg3	RGD:1308089 (Rat Genome Database) 314249 (Entrez Gene) Plekhg3 (Alliance of Genome Resources)	Chr6 q24			NP_001418837 (RefSeq) NM_001431908 (RefSeq)
zebrafish	plekhg2	ZDB-GENE-090819-1 (Zebrafish Model Organism Database) 565988 (Entrez Gene) plekhg2 (Alliance of Genome Resources)	Chr15			XP_068074898 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.