Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DUOX2	HGNC:13273 (HGNC) 50506 (Entrez Gene) 606759 (OMIM) DUOX2 (Alliance of Genome Resources)	Chr15 q21.1	Chr15:45092650-45114172 (-) GRCh38	congenital hypothyroidism thyroid dyshormonogenesis 6	Q9NRD8 (UniProt | EBI) NM_001363711 (RefSeq)
mouse	Duox2	MGI:3036280 (MGI) 214593 (Entrez Gene) Gene Tree Duox2 (Alliance of Genome Resources)	Chr2 60.61 cM	Chr2:122109728-122128930 (-) GRCm39	congenital hypothyroidism	ENSMUSG00000068452 (Ensembl Gene Model) ENSMUSP00000158204 (Ensembl) ENSMUST00000237546 (Ensembl)
rat	Duox2	RGD:628761 (Rat Genome Database) 79107 (Entrez Gene) Duox2 (Alliance of Genome Resources)	Chr3 q35			Q9ES45 (UniProt | EBI) NM_024141 (RefSeq)
zebrafish	duox	ZDB-GENE-091117-14 (Zebrafish Model Organism Database) 565097 (Entrez Gene) duox (Alliance of Genome Resources)	Chr25			XP_017209762 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.