Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GUCY2C	HGNC:4688 (HGNC) 2984 (Entrez Gene) 601330 (OMIM) GUCY2C (Alliance of Genome Resources)	Chr12 p12.3	Chr12:14612632-14696599 (-) GRCh38	congenital diarrhea 6	P25092 (UniProt | EBI) NM_004963 (RefSeq)
mouse	Gucy2c	MGI:106903 (MGI) 14917 (Entrez Gene) Gene Tree Gucy2c (Alliance of Genome Resources)	Chr6 66.67 cM	Chr6:136674282-136758740 (-) GRCm39	abdominal obesity-metabolic syndrome obesity	14917 (NCBI Gene Model) Q3UWA6 (UniProt | EBI) NM_001127318 (RefSeq)
rat	Gucy2c	RGD:2771 (Rat Genome Database) 25711 (Entrez Gene) Gucy2c (Alliance of Genome Resources)	Chr4 q43			P23897 (UniProt | EBI) NM_013170 (RefSeq)
zebrafish	gucy2ca	ZDB-GENE-091118-67 (Zebrafish Model Organism Database) 572052 (Entrez Gene) gucy2ca (Alliance of Genome Resources)	Chr3			XP_009297342 (RefSeq)
	gucy2cb	ZDB-GENE-130531-31 (Zebrafish Model Organism Database) 568219 (Entrez Gene) gucy2cb (Alliance of Genome Resources)	Chr12			XP_068080857 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.