Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CD40LG	HGNC:11935 (HGNC) 959 (Entrez Gene) 300386 (OMIM) CD40LG (Alliance of Genome Resources)	ChrX q26.3	ChrX:136648158-136660390 (+) GRCh38	antiphospholipid syndrome autoimmune thrombocytopenic purpura CD40 ligand deficiency combined T cell and B cell immunodeficiency coronary artery disease dysgammaglobulinemia follicular lymphoma Graves' disease human immunodeficiency virus infectious disease Kawasaki disease lupus nephritis multiple myeloma	P29965 (UniProt | EBI) NM_000074 (RefSeq)
mouse	Cd40lg	MGI:88337 (MGI) 21947 (Entrez Gene) Gene Tree Cd40lg (Alliance of Genome Resources)	ChrX 31.21 cM	ChrX:56257503-56269402 (+) GRCm39	inflammatory bowel disease systemic lupus erythematosus	ENSMUSG00000031132 (Ensembl Gene Model) ENSMUSP00000033466 (Ensembl) ENSMUST00000033466 (Ensembl)
rat	Cd40lg	RGD:708418 (Rat Genome Database) 84349 (Entrez Gene) Cd40lg (Alliance of Genome Resources)	ChrX q36			Q9Z2V2 (UniProt | EBI) NM_053353 (RefSeq)
zebrafish	cd40lg	ZDB-GENE-100727-1 (Zebrafish Model Organism Database) 793819 (Entrez Gene) cd40lg (Alliance of Genome Resources)	Chr14			NP_001138281 (RefSeq) NM_001144809 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.