Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ARHGEF6	HGNC:685 (HGNC) 9459 (Entrez Gene) 300267 (OMIM) ARHGEF6 (Alliance of Genome Resources)	ChrX q26.3	ChrX:136665547-136780932 (-) GRCh38	intellectual disability	Q15052 (UniProt | EBI) NM_001306177 (RefSeq)
mouse	Arhgef6	MGI:1920591 (MGI) 73341 (Entrez Gene) Gene Tree Arhgef6 (Alliance of Genome Resources)	ChrX 31.26 cM	ChrX:56276845-56384089 (-) GRCm39		ENSMUSG00000031133 (Ensembl Gene Model) ENSMUSP00000033468 (Ensembl) ENSMUST00000033468 (Ensembl)
rat	Arhgef6	RGD:1359674 (Rat Genome Database) 363509 (Entrez Gene) Arhgef6 (Alliance of Genome Resources)	ChrX q36			Q5XXR3 (UniProt | EBI) NM_001005565 (RefSeq)
zebrafish	arhgef6	ZDB-GENE-101013-2 (Zebrafish Model Organism Database) 558288 (Entrez Gene) arhgef6 (Alliance of Genome Resources)	Chr14			XP_005173279 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.