Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTPRB	HGNC:9665 (HGNC) 5787 (Entrez Gene) 176882 (OMIM) PTPRB (Alliance of Genome Resources)	Chr12 q15	Chr12:70515870-70637440 (-) GRCh38	angiosarcoma brain glioma breast angiosarcoma colorectal carcinoma glioblastoma lung non-small cell carcinoma sarcoma	P23467 (UniProt | EBI) NM_001109754 (RefSeq)
mouse	Ptprb	MGI:97809 (MGI) 19263 (Entrez Gene) Gene Tree Ptprb (Alliance of Genome Resources)	Chr10 64.68 cM	Chr10:116111428-116225440 (+) GRCm39		ENSMUSG00000020154 (Ensembl Gene Model) ENSMUSP00000151821 (Ensembl) ENSMUST00000218553 (Ensembl)
rat	Ptprb	RGD:1305922 (Rat Genome Database) 314843 (Entrez Gene) Ptprb (Alliance of Genome Resources)	Chr7 q22			NP_001359063 (RefSeq) NM_001429500 (RefSeq)
zebrafish	ptprb	ZDB-GENE-101108-3 (Zebrafish Model Organism Database) 100149130 (Entrez Gene) ptprb (Alliance of Genome Resources)	Chr4			NP_001303656 (RefSeq) NM_001199134 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.