Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GRM8	HGNC:4600 (HGNC) 2918 (Entrez Gene) 601116 (OMIM) GRM8 (Alliance of Genome Resources)	Chr7 q31.33	Chr7:126438598-127253093 (-) GRCh38	alcohol dependence attention deficit hyperactivity disorder autistic disorder schizophrenia	O00222 (UniProt | EBI) NM_000845 (RefSeq)
mouse	Grm8	MGI:1351345 (MGI) 14823 (Entrez Gene) Gene Tree Grm8 (Alliance of Genome Resources)	Chr6 11.97 cM	Chr6:27275120-28135094 (-) GRCm39		14823 (NCBI Gene Model) P47743 (UniProt | EBI) NM_001361125 (RefSeq)
rat	Grm8	RGD:619858 (Rat Genome Database) 60590 (Entrez Gene) Grm8 (Alliance of Genome Resources)	Chr4 q22			P70579 (UniProt | EBI) NM_022202 (RefSeq)
zebrafish	grm8a	ZDB-GENE-110421-2 (Zebrafish Model Organism Database) 792371 (Entrez Gene) grm8a (Alliance of Genome Resources)	Chr4			NP_001289157 (RefSeq) NM_001302228 (RefSeq)
	grm8b	ZDB-GENE-110421-3 (Zebrafish Model Organism Database) 569768 (Entrez Gene) grm8b (Alliance of Genome Resources)	Chr25			NP_001274468 (RefSeq) NM_001287539 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.