Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PF4	HGNC:8861 (HGNC) 5196 (Entrez Gene) 173460 (OMIM) PF4 (Alliance of Genome Resources)	Chr4 q13.3	Chr4:73980811-73982124 (-) GRCh38	multiple myeloma	P02776 (UniProt | EBI) NM_002619 (RefSeq)
	PF4V1	HGNC:8862 (HGNC) 5197 (Entrez Gene) 173461 (OMIM) PF4V1 (Alliance of Genome Resources)	Chr4 q13.3	Chr4:73853296-73854483 (+) GRCh38		P10720 (UniProt | EBI) NM_002620 (RefSeq)
mouse	Pf4	MGI:1888711 (MGI) 56744 (Entrez Gene) Gene Tree Pf4 (Alliance of Genome Resources)	Chr5 44.78 cM	Chr5:90920362-90921242 (+) GRCm39		56744 (NCBI Gene Model) Q9Z126 (UniProt | EBI) NM_019932 (RefSeq)
rat	Pf4	RGD:3305 (Rat Genome Database) 360918 (Entrez Gene) Pf4 (Alliance of Genome Resources)	Chr14			P06765 (UniProt | EBI) NM_001007729 (RefSeq)
zebrafish	cxcl8b.3	ZDB-GENE-111004-1 (Zebrafish Model Organism Database) 100003859 (Entrez Gene) cxcl8b.3 (Alliance of Genome Resources)	Chr7			NP_001108540 (RefSeq) NM_001115068 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.